منابع مشابه
Targeting p110gamma in gastrointestinal cancers: attack on multiple fronts
Phosphoinositide 3-kinases (PI3Ks) regulate several cellular functions that are critical for cancer progression and development, including cell survival, proliferation and migration. Three classes of PI3Ks exist with the class I PI3K encompassing four isoforms of the catalytic subunit known as p110α, p110β, p110γ, and p110δ. Although for many years attention has been mainly focused on p110α rec...
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ژورنال
عنوان ژورنال: Nature
سال: 2004
ISSN: 0028-0836,1476-4679
DOI: 10.1038/430930a